AG Scientific/Aphidicolin/5 mg/355.69,AG Scientific,,AG Scientific,agscientific,AG-scientific,AG Scientific产品目录价格 AG-scientific BESTATIN HCl,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：AG Scientific/Aphidicolin/5 mg/355.69

产品编号：355.69

市场价：¥0.00

场地：美国(厂家直采)

产品分类：生化试剂>其他>其他试剂>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：待定

品牌： AG Scientific

公司：AG Scientific, Inc.,

公司分类：

商品介绍

More Information

Alternate Name/Synonyms

APC; ICI 69653; NSC 234714

SKU

A-1026

CAS #

38966-21-1

Chemical Name

(1S,2S,5R,6R,7R,10S,12R,13R)-6,13-bis(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol

Chemical Formula

C₂₀H₃₄O₄

Molecular Weight

338.5 Da

Appearance

White Powder

Purity

>99% (TLC)

Solubility

Methanol: Clear colorless solution at 10 mg/ml

Melting Point

230°C

Preparation

N/A

Storage Temp

+4°C

THERAPEUTIC AREA

Not Available

USE

For research use only. Not intended for diagnostic or therapeutic use. Aphidicolin is a tetracyclic diterpene with antibiotic, antiviral and antimitotic properties by blocking the cell cycle at early S-phase. This property has been used to synchronise cell division and is useful as a tool in cell differentiation research. Aphidicolin induces apoptosis, prolongs the half-life of DNA methyltransferase, is active against Leishmania parasites and acts synergistically with the antitumor agents, vincristine and doxorubicin.

Merck Index

Merck Index: 13.734.2001

MDL NUMBER

MFCD00083214

CHEMACX

X1001937-7

INCHI

InChI=1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1

SMILES

C[C@]12CC[C@H]([C@@]([C@@H]1CC[C@@H]3[C@@]24CC[C@@]([C@H](C3)C4)(CO)O)(C)CO)O

Peptide sequence

Not Applicable

RTECS

PB9185000

UN #'S

Not Applicable

PACKING GROUP

Not Applicable

HAZARD CLASS

Not Applicable

Handling

Warning.Toxic. Potential Carcinogenic. Do not use this compound if you are not fully trained or are unaware of the hazards involved. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Avoid contact with skin, eyes or clothing. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilation.

Citations

CELL BIOLOGY:Sororin cooperates with the acetyltransferase Eco2 to ensure DNA replication-dependent sister chromatid cohesionAndrea L. Lafont, Jianhua Song, and Susannah RankinPNAS, Nov 2010; 107: 20364 - 20369.

Citations_Hyperlink

http://www.pnas.org/cgi/reprint/107/47/20364

Certificate of Analysis 1

A-1026, J1034E.pdf

Certificate of Analysis 2

A-1026, J1034D.pdf

Certificate of Analysis 3

A-1026, J1034C.pdf

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