More Information
Alternate Name/Synonyms
Calcium Ionophore A23187; Calcimycin; Antibiotic A23187; Calcium Ionophore
Chemical Name
5-(methylamino)-2-[[(2S,3R,5R,6S,8R,9R)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid
Chemical Formula
C29H37N3O6
Molecular Weight
523.60 Da
Solubility
DMSO, methanol, dicholormethane. Slightly soluble in water.
THERAPEUTIC AREA
Infectious Diseases
USE
A23187 has antibiotic properties against gram positive bacteria and fungi. Calcium ionophore.
INCHI
InChI=1S/C29H37N3O6/c1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35/h6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35)/t15-,16+,17+,18?,22-,27-,29?/m0/s1
SMILES
C[C@H]1CCC2([C@@H](C[C@H]([C@H](O2)C(C)C(=O)c3ccc[nH]3)C)C)O[C@H]1Cc4nc5c(o4)ccc(c5C(=O)O)NC
Peptide sequence
Not Applicable
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product
Citations
MECHANISMS OF SIGNAL TRANSDUCTION:Identification of Nitric Oxide as an Endogenous Activator of the AMP-activated Protein Kinase in Vascular Endothelial CellsJunhua Zhang, Zhonglin Xie, Yunzhou Dong, Shuangxi Wang, Chao Liu, and Ming-Hui ZouJ. Biol. Chem., Oct 2008; 283: 27452 - 27461.
Citations_Hyperlink
http://www.jbc.org/cgi/reprint/283/41/27452
msds 1
A-1020, A2318, SDS, diamond format.pdf
Certificate of Analysis 1
A-1020, G1328B.pdf
Certificate of Analysis 2
A-1020, G1328.pdf
Certificate of Analysis 3
A-1020, G1239.pdf
AG Scientific常用产品报价单
产品名 | 货号 | 公司分类 | 商城分类 | 美金价 |
AG Scientific/Proteinase K/500 mg/199.99 | 199.99 | AG Scientific, Inc. | 蛋白酶类 | 0.00 |
AG Scientific/Proteinase K/50 mg/39.99 | 39.99 | AG Scientific, Inc. | 其他试剂 | 0.00 | AG Scientific/Proteinase K/100 mg/59.99 | 59.99 | AG Scientific, Inc. | 单克隆抗体 | 0.00 | AG Scientific/Proteinase K (Recombinant), Molecular/PCR Grade/1 g/537.62 | 537.62 | AG Scientific, Inc. | 琼脂糖 | 0.00 | AG Scientific/Proteinase K Solution (20 mg/mL)/5 ml/123.29 | 123.29 | AG Scientific, Inc. | 刺激/抑制试剂 | 0.00 |