More Information
Alternate Name/Synonyms
Flagecidin; (-)-Anisomycin; Anhydroscopin A; NSC 76712; (2R,3S,4S)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate; (2R,3S,4S)-2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate; 2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate
Chemical Name
[(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate
Chemical Formula
C14H19NO4
Molecular Weight
265.31 Da
Appearance
White crystalline powder
Solubility
Soluble in DMSO
Storage Temp
Store desiccated at +4° C
THERAPEUTIC AREA
Psychological Disorders, Infectious Diseases
USE
For research use only. Not for human or drug use. Anisomycin interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. Anisomycin is also mentioned as a potential psychiatric drug, as it may inhibit the consolidation of new context-specific long-term memories, as well as long time consolidated memories rendered labile through reactivation.
INCHI
InChI=1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m0/s1
SMILES
CC(=O)O[C@H]1[C@@H](CN[C@H]1Cc2ccc(cc2)OC)O
UN #"S
UN 2811, 2941.90.1050
Handling
Protect from light and moisture. Warning: very ToxicAvoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilatio
Citations
RESEARCH:Aversive olfactory learning and associative long-term memory in Caenorhabditis elegansHisayuki Amano and Ichiro N. MaruyamaLearn. Mem., Sep 2011; 18: 654 - 665.
Citations_Hyperlink
http://learnmem.cshlp.org/cgi/reprint/18/10/654
msds 1
A-1049, Anisomycin, SDS, diamond format.pdf
Certificate of Analysis 1
A-1049, J1289.pdf
Certificate of Analysis 2
A-1049, H1392B.pdf
Certificate of Analysis 3
A-1049, H1392A.pdf
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