AG Scientific/17-AAG/5 mg/154.66,AG Scientific,,AG Scientific,agscientific,AG-scientific,中国agscientific公司 AG-scientific盐酸贝斯他汀,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：AG Scientific/17-AAG/5 mg/154.66

产品编号：154.66

市场价：¥0.00

场地：美国(厂家直采)

产品分类：蛋白类>酶>蛋白酶类>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：待定

品牌： AG Scientific

公司：AG Scientific, Inc.,

公司分类：

商品介绍

MoreInformation

AlternateName/Synonyms

Tanespimycin;17-Allylaminogeldanamycin;

SKU

A-1256

CAS#

75747-14-7

ChemicalName

[(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azABIcyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl]carbamate

ChemicalFormula

C₃₁H₄₃N₃O₈

MolecularWeight

585.7Da

Appearance

PurplePowder

Purity

>99%

Solubility

DMSO,Methanol:Clearpurplesolutionat10mg/ml

MeltingPoint

207-208°C

Preparation

N/A

StorageTemp

-20°C

THERAPEUTICAREA

OncologicalDisorders

USE

Forresearchuseonly.Notintendedfordiagnosticortherapeuticuse.17-AAGisaderivativeoftheantibioticgeldanamycinthatisbeingstudiedinthetreatmentofcancer,specificallyinyoungerpatientswithcertaintypesofleukemiaorsolidtumors,especiallykidneytumors.ItworksbyinhibitingHsp90,whichisexpressedinthosetumors.

MerckIndex

N/A

MDLNUMBER

MFCD04973892

CHEMACX

X1367336-8

INCHI

InChI=1S/C31H43N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-11,15-17,19,24-25,27,29,33,36H,1,12-14H2,2-7H3,(H2,32,39)(H,34,38)/b11-9-,18-10-,20-15-/t17-,19+,24+,25+,27-,29+/m1/s1

SMILES

C[C@H]1C[C@@H]([C@@H]([C@H](/C=C([C@@H]([C@H](/C=CC=C(/C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)/C)C)O)OC

RTECS

NotApplicable

UN#"S

NotApplicable

Handling

Avoidcontactwithskin,eyesorclothing.Usepersonalprotectiveequipmentasrequired.Washcontaminatedclothingbeforereuse.Donotbreathedust/fume/gas/mist/vapors/spray.Donoteat,drinkorsmokewhenusingthisproduct.Usewithlocalexhaustventilation

Citations

CLINICALINVESTIGATIONS:PharmacokineticAssessmentoftheUptakeof16β-18F-Fluoro-5-Dihydrotestosterone(FDHT)inProstateTumorsasMeasuredbyPETBradleyJ.Beattie,PeterM.Smith-Jones,YuliyaS.Jhanwar,HeikoSchöder,C.RossSchmidtlein,MichaelJ.Morris,PatZanzonico,OliviaSquire,GustavoS.P.Meirelles,RonFinn,MohammadNamavari,ShangdeCai,HowardI.Scher,StevenM.Larson,andJohnL.HummJ.Nucl.Med.,Feb2010;51:183-192.

Citations_Hyperlink

http://jnm.snmjournals.org/content/51/2/183.full.pdf+html

MSDs1

A-1256,17-AAG,SDS,diamondformat.pdf

CertificateofAnalysis1

A-1256,E1348H.pdf

CertificateofAnalysis2

A-1256,E1348G.pdf

CertificateofAnalysis3

A-1256,E1348F.pdf

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