AG Scientific/Mycophenolic Acid, MPA/M-1036/1 g,AG Scientific,,AG Scientific,agscientific,AG-scientific,进口试剂AG Scientific直采美国AG公司,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：AG Scientific/Mycophenolic Acid, MPA/M-1036/1 g

产品编号：M-1036-1g

市场价：¥7469.60

场地：美国(厂家直采)

产品分类：细胞相关>细胞培养>刺激/抑制试剂>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$373.48

品牌： AG Scientific

公司：AG Scientific, Inc.,

公司分类：

商品介绍

Immunosuppressive agent. Mycophenolic acid (MPA) has been tested extensively in renal transplant patients and has been shown to be effective in reducing the incidence of acute graft rejection. MPA is now being evaluated in combinations with tacrolimus. It selectively inhibits lymphocyte proliferation by blocking the enzyme, inosine monophosphate dehydrogenase, part of in the guanosine monophosphate pathway.

This enzyme is involved in the de novo synthesis of purine nucleotides¹.

1.) Methanol-Associated Matrix Effects in Electrospray Ionization Tandem Mass Spectrometry.Quantification of Mycophenolic Acid and Glucuronide Metabolite in Human Serum by HPLC-Tandem Mass Spectrometry.

Additional Information

Synonyms	MPA, mycophenolate mofetil (MMF)
Product #	M-1036
CAS #	24280-93-1
Chemical Name	6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Formula	C₁₇H₂₀O₆
MW	320.3
Appearance	White to off-white Powder
Purity	98%
Solubility	Soluble in ethanol (>10 mg/ml), DMSO (20 mg/ml), DMF (30 mg/ml), and 1:1 DMSO:PBS (pH 7.2) (~0.5 mg/ml). Insoluble in water
Melting Point	141°C
Boiling Point	611.61 °C at 760 mmHg
Storage Temp	+4°C
Therapeutic Area	Autoimmune Diseases
Use	Mycophenolic acid is an immunosuppressant drug used to prevent rejection in organ transplantation

Additional Information

Merck Index	13.6352.2001
MDL Number	MFCD00036814
ChemACX	X1002405-4
InChI	InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)
SMILES	Cc1c2c(c(c(c1OC)CC=C(C)CCC(=O)O)O)C(=O)OC2

品牌介绍

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